
MEMBERS FUNDING ANNOUNCEMENTS.
Global collaboration action for the development of vaccines for reducing the disease burden of Tuberculosis in sub-Saharan Africa
Issued by: Horizon Europe (HORIZON)
Notice Number: HORIZON-JU-GH-EDCTP3-2025-01-two-stage
Opening Date: January 30, 2025
Deadlines: March 20, 2025 | September 02, 2025
The actions funded under this topic should contribute to increased international cooperation among researchers and funders, catalyse research synergies, and leverage resources and investments in order to achieve the reduction of disease burden in SSA through the development of vaccines.
Proposals are expected to include the effective in-kind and/or financial contribution of contributing partners, in order to produce meaningful and significant effects enhancing the impact of the related research activities.
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This topic aims at supporting activities that contribute to one or several of the expected impacts for this call. To that end, proposals submitted under this topic should aim for delivering results that are directed, tailored towards and contributing to at least two of the following expected outcomes, with the first being mandatory:
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Obtain evidence of immunogenicity, efficacy, safety or clinical utility on vaccine candidates under development and licensed vaccine(s);
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Generate clinical data on TB prophylactic vaccines serving adolescents and adults, and including where appropriate pregnant and lactating women, new-borns, children, other vulnerable and neglected populations, and people with co-infections and co-morbidities at risk in SSA;
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Contribute to the data package related to immunisation/vaccination enabling public health authorities and policy makers to recommend on vaccination strategies, publish updated or new evidence-based clinical guidelines and best practices or design tailor-made TB policies targeting SSA.
Notice of Special Interest (NOSI): Mechanisms of Mycobacterial-Induced Immunity in HIV-Infected and/or Uninfected Individuals to Inform Innovative Tuberculosis Vaccine Design
Issued by: National Institute of Allergy and Infectious Diseases (NIAID)
Release date: September 20, 2020
Expiration date: January 08, 2023
The purpose of this Notice of Special Interest (NOSI) is to stimulate innovative studies to identify and understand the immune responses that mediate protection from Mycobacterium tuberculosis (Mtb) infection or progression to active tuberculosis (TB) disease. Studies may focus on any stage of mycobacterial infection or following vaccination with Bacillus Calmette-Guérin (BCG) or investigational TB vaccines and may include HIV-infected or uninfected individuals.
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Research supported under this NOSI should go beyond descriptive information currently known about Mtb infection, immune responses to TB vaccines, or immune modulation by non-tuberculous mycobacterial (NTM) infection, or by HIV/AIDS. Applications that include characterization of the timing, anatomical location, and contribution to disease outcome, of mucosal and/or systemic immune responses to mycobacterial infection and/or vaccination are sought. This research is expected to advance understanding of immune mechanisms in Mtb infection/vaccination and contribute to the advancement of new TB vaccines, including in populations also infected with HIV.
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Posted: December 17, 2020
Call for tenders HADEA/2023/OP/0036: Speed up the development of and access to innovative medical countermeasures
Issued by: Health Emergency Preparedness and Response Authority (HERA)
Notice Number: HADEA/2023/OP/0036
First Available Due Date: September 22, 2023
Expiration date: December 04, 2023
This call for tenders aims at purchasing services to speed up the development of and support the access to medical countermeasures which address HERA’s priority threats. To accelerate development and support access to MCMs, the requested services include the provision of clinical and concurrent non-clinical development services and the priority right to purchase the promising products (Investigational Medicinal Product – IMP for lots 1, 2 and 3 and product for lot 4), that shall allow bringing innovative products to the market and ensure EU/EEA access to them.
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Release date: September 22, 2023